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Research ArticleOriginal Research

Humidification and Secretion Volume in Mechanically Ventilated Patients

Mario Solomita, Lucy B Palmer, Feroza Daroowalla, Jeffrey Liu, Dori Miller, Deniese S LeBlanc and Gerald C Smaldone
Respiratory Care October 2009, 54 (10) 1329-1335;
Mario Solomita
Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook.
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Lucy B Palmer
Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook.
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Feroza Daroowalla
Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook.
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Jeffrey Liu
Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook.
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Dori Miller
Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook.
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Deniese S LeBlanc
Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook.
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Gerald C Smaldone
Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook.
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  • For correspondence: [email protected]
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Abstract

OBJECTIVE: To determine potential effects of humidification on the volume of airway secretions in mechanically ventilated patients.

METHODS: Water vapor delivery from devices providing non-heated-wire humidification, heated-wire humidification, and heat and moisture exchanger (HME) were quantified on the bench. Then, patients requiring 24-hour mechanical ventilation were exposed sequentially to each of these humidification devices, and secretions were removed and measured by suctioning every hour during the last 4 hours of the 24-hour study period.

RESULTS: In vitro water vapor delivery was greater using non-heated-wire humidification, compared to heated-wire humidification and HME. In vivo, a total of 9 patients were studied. Secretion volume following humidification by non-heated-wire humidification was significantly greater than for heated-wire humidification and HME (P = .004).

CONCLUSIONS: The volume of secretions appeared to be linked to humidification, as greater water vapor delivery measured in vitro was associated with greater secretion volume in vivo.

  • humidifier
  • ventilation
  • sputum
  • relative humidity
  • heat and moisture exchange
  • mechanical ventilation

Footnotes

  • Correspondence: Gerald C Smaldone MD PhD, Department of Pulmonary and Critical Care Medicine, Stony Brook University Medical Center, State University of New York at Stony Brook, HSC T 17-040, Stony Brook NY 11794. E-mail: gsmaldone{at}notes.cc.sunysb.edu.
  • Dr Smaldone has disclosed a relationship with Pari Respiratory Equipment. The other authors have disclosed no conflicts of interest.

  • Copyright © 2009 by Daedalus Enterprises Inc.
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Respiratory Care: 54 (10)
Respiratory Care
Vol. 54, Issue 10
1 Oct 2009
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Humidification and Secretion Volume in Mechanically Ventilated Patients
Mario Solomita, Lucy B Palmer, Feroza Daroowalla, Jeffrey Liu, Dori Miller, Deniese S LeBlanc, Gerald C Smaldone
Respiratory Care Oct 2009, 54 (10) 1329-1335;

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Humidification and Secretion Volume in Mechanically Ventilated Patients
Mario Solomita, Lucy B Palmer, Feroza Daroowalla, Jeffrey Liu, Dori Miller, Deniese S LeBlanc, Gerald C Smaldone
Respiratory Care Oct 2009, 54 (10) 1329-1335;
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Keywords

  • humidifier
  • ventilation
  • sputum
  • relative humidity
  • heat and moisture exchange
  • mechanical ventilation

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