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Research ArticleOriginal Research

Effect of Albuterol on Expiratory Resistance in Mechanically Ventilated Patients

Eumorfia Kondili, Christina Alexopoulou, George Prinianakis, Nektaria Xirouchaki, Katerina Vaporidi and Dimitris Georgopoulos
Respiratory Care May 2011, 56 (5) 626-632; DOI: https://doi.org/10.4187/respcare.00984
Eumorfia Kondili
Department of Intensive Care Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece.
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  • For correspondence: konde@med.uoc.gr
Christina Alexopoulou
Department of Intensive Care Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece.
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George Prinianakis
Department of Intensive Care Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece.
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Nektaria Xirouchaki
Department of Intensive Care Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece.
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Katerina Vaporidi
Department of Intensive Care Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece.
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Dimitris Georgopoulos
Department of Intensive Care Medicine, University Hospital of Heraklion, University of Crete, Heraklion, Crete, Greece.
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    Fig. 1.

    Flow-volume and post-occlusion tracheal pressure-volume curves during passive expiration in a representative patient. We divide the curves into 5 equal slices. The long arrow indicates the direction of expiration. The time constant and dynamic effective compliance of slice 1 is obtained by analyzing the flow-volume and pressure-volume relationships of the data from that slice.

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    Fig. 2.

    Relationship between albuterol-induced changes in the time constant of the total system (respiratory system, endotracheal tube, ventilator circuit, the change in the time constant, and the expiratory resistance of the respiratory system (ΔRRS) at each volume slice. The arrows indicate patients in whom the albuterol-induced change in the change in the time constant was in the opposite direction of ΔRRS.

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Respiratory Care: 56 (5)
Respiratory Care
Vol. 56, Issue 5
1 May 2011
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Effect of Albuterol on Expiratory Resistance in Mechanically Ventilated Patients
Eumorfia Kondili, Christina Alexopoulou, George Prinianakis, Nektaria Xirouchaki, Katerina Vaporidi, Dimitris Georgopoulos
Respiratory Care May 2011, 56 (5) 626-632; DOI: 10.4187/respcare.00984

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Effect of Albuterol on Expiratory Resistance in Mechanically Ventilated Patients
Eumorfia Kondili, Christina Alexopoulou, George Prinianakis, Nektaria Xirouchaki, Katerina Vaporidi, Dimitris Georgopoulos
Respiratory Care May 2011, 56 (5) 626-632; DOI: 10.4187/respcare.00984
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Keywords

  • COPD
  • expiratory resistance
  • mechanical ventilation
  • bronchodilators
  • albuterol

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