Abstract
This article reviews the common pulmonary complications seen in the pediatric oncology population and our approach to diagnosis, management, and therapy considerations in this specialized population, including patients receiving chemotherapy, radiation, and hematopoietic stem cell transplantation. Although infections cause the most significant complications in this population, non-infectious complications, including acute lung injury from chemotherapy or radiation, idiopathic interstitial pneumonia, diffuse alveolar hemorrhage, bronchiolitis obliterans, and cryptogenic organizing pneumonia, also occur commonly. With improvements in survival of childhood cancer, there are now a growing number of adults who are childhood cancer survivors who may be encountered by therapists in adult hospitals. We also review the growing literature on the emerging late pulmonary findings in these adult childhood cancer survivors.
- childhood cancer
- chemotherapy
- radiation
- hematopoietic stem cell transplantation
- interstitial pneumonia
- pulmonary hemorrhage
- bronchiolitis oblterans
- pnemonia
Footnotes
- Correspondence: Dennis C Stokes MD MPH, University of Tennessee Health Science Center College of Medicine, 49 North Dunlap, Memphis, TN 38103. E-mail: dstokes4{at}uthsc.edu.
The authors have disclosed no conflicts of interest.
Dr Stokes presented a version of this paper at the 55th Respiratory Care Journal Conference, “Pediatric Respiratory Care,” held June 10-11, 2016, in St Petersburg, Florida.
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