Validity of Empirical Estimates of the Ratio of Dead Space to Tidal Volume in ARDS

REFERENCES

1. 1.↵
   1. Radermacher P,
   2. Maggiore SM,
   3. Mercat A

   . Fifty years of research in ARDS. Gas exchange in acute respiratory distress syndrome. Am J Respir Crit Care Med 2017;196(8):964-984.

   OpenUrlCrossRef
2. 2.↵
   1. Matthay MA,
   2. Ware LB,
   3. Zimmerman GA

   . The acute respiratory distress syndrome. J Clin Invest 2012;122(8):2731-2740.

   OpenUrlCrossRefPubMedWeb of Science
3. 3.↵
   1. Blanch L,
   2. López-Aguilar J,
   3. Lucangelo U

   . Dead space in acute respiratory distress syndrome: more than a feeling! Crit Care 2016;20(1):214.

   OpenUrl
4. 4.↵
   1. Coffey RL,
   2. Albert RK,
   3. Robertson HT

   . Mechanisms of physiological dead space response to PEEP after acute oleic acid lung injury. J Appl Physiol Respir Environ Exerc Physiol 1983;55(5):1550-1557.

   OpenUrlPubMedWeb of Science
5. 5.↵
   1. Nuckton TJ,
   2. Alonso JA,
   3. Kallet RH,
   4. Daniel BM,
   5. Pittet J-F,
   6. Eisner MD,
   7. et al

   . Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med 2002;346(17):1281-1286.

   OpenUrlCrossRefPubMedWeb of Science
6. 6.↵
   1. Kallet RH,
   2. Zhuo H,
   3. Liu KD,
   4. Calfee CS,
   5. Matthay MA

   , National Heart Lung and Blood Institute ARDS Network Investigators. The association between physiologic dead-space fraction and mortality in subjects with ARDS enrolled in a prospective multi-center clinical trial. Respir Care 2014;59(11):1611-1618.

   OpenUrlAbstract/FREE Full Text
7. 7.↵
   1. Lucangelo U,
   2. Bernabè F,
   3. Vatua S,
   4. Degrassi G,
   5. Villagrà A,
   6. Fernandez R,
   7. et al

   . Prognostic value of different dead space indices in mechanically ventilated patients with acute lung injury and ARDS. Chest 2008;133(1):62-71.

   OpenUrlCrossRefPubMedWeb of Science
8. 8.↵
   1. Goligher EC,
   2. Combes A,
   3. Brodie D,
   4. Ferguson ND,
   5. Pesenti AM,
   6. Ranieri VM,
   7. et al

   . Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design. Intensive Care Med 2019;45(9):1219-1230.

   OpenUrl
9. 9.↵
   1. Kallet RH,
   2. Daniel BM,
   3. Garcia O,
   4. Matthay MA

   . Accuracy of physiologic dead space measurements in patients with acute respiratory distress syndrome using volumetric capnography: comparison with the metabolic monitor method. Respir Care 2005;50(4):462-467.

   OpenUrlAbstract/FREE Full Text
10. 10.↵
    1. Suarez-Sipmann F,
    2. Blanch L

    . Physiological markers for acute respiratory distress syndrome: let’s get more efficient! Am J Respir Crit Care Med 2019;199(3):260-261.

    OpenUrl
11. 11.↵
    1. Siddiki H,
    2. Kojicic M,
    3. Li G,
    4. Yilmaz M,
    5. Thompson TB,
    6. Hubmayr RD,
    7. Gajic O

    . Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials. Crit Care 2010;14(4):R141.

    OpenUrlCrossRefPubMed
12. 12.↵
    1. Beitler JR,
    2. Thompson BT,
    3. Matthay MA,
    4. Talmor D,
    5. Liu KD,
    6. Zhuo H

    . Estimating dead-space fraction for secondary analyses of acute respiratory distress syndrome clinical trials. Crit Care Med 2015;43(5):1026-1035.

    OpenUrl
13. 13.↵
    1. Charron C,
    2. Repesse X,
    3. Bouferrache K,
    4. Bodson L,
    5. Castro S,
    6. Page B,
    7. et al

    . PaCO2 and alveolar dead space are more relevant than PaO2/FiO2 ratio in monitoring the respiratory response to prone position in ARDS patients: a physiological study. Crit Care 2011;15(4):R175.

    OpenUrlCrossRefPubMed
14. 14.↵
    1. Matthay MA,
    2. Brower RG,
    3. Carson S,
    4. Douglas IS,
    5. Eisner M,
    6. Hite D,
    7. et al

    . Randomized, placebo-controlled clinical trial of an aerosolized β2-agonist for treatment of acute lung injury. Am J Resp Crit Care 2011;184(5):561-568.

    OpenUrlCrossRefPubMedWeb of Science
15. 15.↵
    1. Suarez-Sipmann F,
    2. Santos A,
    3. Böhm SH,
    4. Borges JB,
    5. Hedenstierna G,
    6. Tusman G

    . Corrections of Enghoff’s dead space formula for shunt effects still overestimate Bohr’s dead space. Resp Physiol Neurobi 2013;189(1):99-105.

    OpenUrl
16. 16.↵
    1. Tusman G,
    2. Gogniat E,
    3. Bohm SH,
    4. Scandurra A,
    5. Suarez-Sipmann F,
    6. Torroba A,
    7. et al

    . Reference values for volumetric capnography-derived non-invasive parameters in healthy individuals. J Clin Monit Comput 2013;27(3):281-288.

    OpenUrlCrossRefPubMed
17. 17.↵
    1. Harris JA,
    2. Benedict FG

    . A biometric study of human basal metabolism. Proc Natl Acad Sci USA 1918;4(12):370-373.

    OpenUrlFREE Full Text
18. 18.↵
    1. Goligher EC,
    2. Amato MBP,
    3. Slutsky AS

    . Applying precision medicine to trial design using physiology: extracorporeal CO2 removal for acute respiratory distress syndrome. Am J Respir Crit Care Med 2017;196(5):558-568.

    OpenUrl
19. 19.↵
    1. Robertson HT

    . Dead space: the physiology of wasted ventilation. Eur Respir J 2015;45(6):1704-1716.

    OpenUrlAbstract/FREE Full Text
20. 20.↵
    1. Gattinoni L,
    2. Carlesso E,
    3. Langer T

    . Towards ultraprotective mechanical ventilation. Curr Opin Anaesthesiol 2012;25(2):141-147.

    OpenUrlCrossRefPubMed
21. 21.↵
    1. Combes A,
    2. Fanelli V,
    3. Pham T,
    4. Ranieri VM

    , the European Society of Intensive Care Medicine Trials Group, and the Strategy of Ultra-Protective Lung Ventilation With Extracorporeal CO2 Removal for New-Onset Moderate to Severe ARDS (SUPERNOVA) Investigators. Feasibility and safety of extracorporeal CO2 removal to enhance protective ventilation in acute respiratory distress syndrome: the SUPERNOVA study. Intensive Care Med 2019;45(5):592-600.

    OpenUrl
22. 22.↵
    1. Seeley E,
    2. McAuley DF,
    3. Eisner M,
    4. Miletin M,
    5. Matthay MA,
    6. Kallet RH

    . Predictors of mortality in acute lung injury during the era of lung protective ventilation. Thorax 2008;63(11):994-998.

    OpenUrlAbstract/FREE Full Text
23. 23.↵
    1. Matthay MA,
    2. Kallet RH

    . Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome. Crit Care 2011;15(5):185.

    OpenUrlPubMed
24. 24.↵
    1. Hedenstierna G,
    2. Sandhagen B

    . Assessing dead space. A meaningful variable? Minerva Anestesiol 2006;72(6):521-528.

    OpenUrlPubMedWeb of Science
25. 25.↵
    1. Doorduin J,
    2. Nollet JL,
    3. Vugts MPAJ,
    4. Roesthuis LH,
    5. Akankan F,
    6. Hoeven JGVD,
    7. et al

    . Assessment of dead-space ventilation in patients with acute respiratory distress syndrome: a prospective observational study. Crit Care 2016;20(1):121.

    OpenUrl
26. 26.↵
    1. Gogniat E,
    2. Ducrey M,
    3. Dianti J,
    4. Madorno M,
    5. Roux N,
    6. Midley A,
    7. et al

    . Dead space analysis at different levels of positive end-expiratory pressure in acute respiratory distress syndrome patietnts. J Crit Care 2018;45:231-238.

    OpenUrl
27. 27.↵
    1. Vasques F,
    2. Sanderson B,
    3. Formenti F,
    4. Shankar-Hari M,
    5. Camporota L

    . Physiological dead space ventilation, disease severity and outcome in ventilated patients with hypoxaemic respiratory failure due to coronavirus disease 2019. Intensive Care Med 2020;46(11):2092-2093.

    OpenUrl