Abstract
Background: Some investigation revealed the association between depression and physical measurements of chronic obstructive pulmonary disease (COPD) patients in North America and Europe but limited studies in Asia were performed.
Methods: In this cross-sectional study, consecutive 84 stable outpatients with COPD (Age: 72.0 ± 9.0. Forced expiratory volume in one second (%predicted) 46 ± 15%. Fifteen females (17.9%)) in a Japanese community based hospital were recruited. “Probable depression” was defined as short form of the geriatric depression scale (SF-GDS) ≥ 6. Relationships among commonly used physical measurements, SF-GDS raw score, and probable depression were evaluated with Spearman's rank correlation test, multiple linear regression analysis, logistic regression analysis, and receiver operating characteristic curve.
Results: Thirty two (38.1%) had probable depression. Body mass index, obstruction, dyspnea, exercise capacity index; forced expiratory volume in one second (%predicted); modified medical research council dyspnea scale; six-minute walk distance; saturation of oxygen on artery by pulse oximetry had followings: (i) simple correlations (|r|:0.42 0.60 , P < .001 for all) for SF GDS raw score, (ii) partial correlations (|r|:0.25 0.51 , P < .05 for all) for SF GDS raw score after adjusting demographic and social factors, (iii) association for probable depression in logistic regression analysis after adjusting demographic and social factors (P < .05 for all), and (iv) area under the receiver operating characteristic curves for probable depression (area under the curves: 0.719-0.841, P < .001 for any),
Conclusions: Physical parameters were associated with depression in our Japanese COPD outpatients.
Footnotes
- Correspondence to: Takeshi Kaneko, M.D., Ph.D. Respiratory Disease Center, Yokohama City University Medical Center 4-57, Urafune, Minami-ku, Yokohama City, 232-0024, Japan Tel.: +80-45-261-5656; Fax: +80-45-241-2812 Email: takeshi{at}med.yokohama-cu.ac.jp
Authors have no conflict-of-interest
- Copyright © 2012 by Daedalus Enterprises Inc.