Abstract
Benign “metastasizing” leiomyoma (BML) was initially used to describe single or multiple pulmonary nodules composed of proliferating smooth muscle cells, lacking cellular atypia, in premenopausal females 3 months to 20 years after hysterectomy for uterine leiomyoma. The lung is the most commonly involved site, thus including many malignant and benign entities in the differential diagnosis. The present article refers to a 47-year-old premenopausal woman with a history of subtotal hysterectomy for a uterine leiomyoma presenting with bilateral cavitating pulmonary nodules. A number of nodules were resected by video-assisted thoracoscopic surgery. The histological findings in correlation with the immunohistochemical results were consistent with the diagnosis of BML. The patient was subjected to bilateral salpingo-oophorectomy combined with complete removal of the remained cervix. One year later, the patient remains asymptomatic and the pulmonary nodules stable in terms of number, size, location and morphology.
Footnotes
- Correspondence: Angeliki Loukeri, MD, Respiratory Intensive Care Unit, Athens Chest Hospital “Sotiria”, Mesogeion 152, 11527, Athens, Greece, Tel. 00302107763439, Fax. 00302107770210, angelouk{at}live.com
Conflicts of interest: None
Financial support: None
- Copyright © 2013 by Daedalus Enterprises Inc.