PT - JOURNAL ARTICLE AU - Nobuyuki Horita AU - Takeshi Kaneko AU - Masaharu Shinkai AU - Makiko Yomota AU - Satoshi Morita AU - Bruce K. Rubin AU - Yoshiaki Ishigatsubo TI - Depression in Japanese Patients with Chronic Obstructive Pulmonary Disease. A Cross-Sectional Study AID - 10.4187/respcare.02065 DP - 2012 Dec 04 TA - Respiratory Care PG - respcare.02065 4099 - http://rc.rcjournal.com/content/early/2012/12/04/respcare.02065.short 4100 - http://rc.rcjournal.com/content/early/2012/12/04/respcare.02065.full AB - Background: Some investigation revealed the association between depression and physical measurements of chronic obstructive pulmonary disease (COPD) patients in North America and Europe but limited studies in Asia were performed. Methods: In this cross-sectional study, consecutive 84 stable outpatients with COPD (Age: 72.0 ± 9.0. Forced expiratory volume in one second (%predicted) 46 ± 15%. Fifteen females (17.9%)) in a Japanese community based hospital were recruited. “Probable depression” was defined as short form of the geriatric depression scale (SF-GDS) ≥ 6. Relationships among commonly used physical measurements, SF-GDS raw score, and probable depression were evaluated with Spearman's rank correlation test, multiple linear regression analysis, logistic regression analysis, and receiver operating characteristic curve. Results: Thirty two (38.1%) had probable depression. Body mass index, obstruction, dyspnea, exercise capacity index; forced expiratory volume in one second (%predicted); modified medical research council dyspnea scale; six-minute walk distance; saturation of oxygen on artery by pulse oximetry had followings: (i) simple correlations (|r|:0.42 0.60 , P < .001 for all) for SF GDS raw score, (ii) partial correlations (|r|:0.25 0.51 , P < .05 for all) for SF GDS raw score after adjusting demographic and social factors, (iii) association for probable depression in logistic regression analysis after adjusting demographic and social factors (P < .05 for all), and (iv) area under the receiver operating characteristic curves for probable depression (area under the curves: 0.719-0.841, P < .001 for any), Conclusions: Physical parameters were associated with depression in our Japanese COPD outpatients.