TY - JOUR T1 - Functional Respiratory Imaging as a Tool to Personalize Respiratory Treatment in Patients With Unilateral Diaphragmatic Paralysis JF - Respiratory Care DO - 10.4187/respcare.02756 SP - respcare.02756 AU - Cedric S Van Holsbeke AU - Glenn Leemans AU - Wim G Vos AU - Jan W De Backer AU - Samir C Vinchurkar AU - Michel Geldof AU - Pascal R Verdonck AU - Paul M Parizel AU - Paul E Van Schil AU - Wilfried A De Backer Y1 - 2014/08/12 UR - http://rc.rcjournal.com/content/early/2014/08/12/respcare.02756.abstract N2 - A completely different treatment approach was chosen for 2 patients with unilateral diaphragmatic paralysis and complaints of dyspnea despite similar anatomic and physiologic abnormalities. These decisions were supported by results obtained by functional respiratory imaging (FRI). FRI generated functional information on lobar ventilation and local drug deposition. In the first patient, some lobes were poorly ventilated, and drug deposition simulation showed that some regions were undertreated. This patient underwent diaphragmatic plication to restore ventilation. In the second patient, all lobes were still ventilated. A conservative approach with regular follow-ups was chosen to wait for spontaneous recovery of the diaphragmatic function. Both patients improved subjectively and objectively. These cases demonstrate how novel medical imaging techniques such as FRI can be used to personalize respiratory treatment in patients with unilateral diaphragmatic paralysis. ER -