PT - JOURNAL ARTICLE AU - Christopher R Gilbert AU - Jennifer W Toth AU - Umar Osman AU - Michael F Reed TI - Endobronchial Valve Placement as Destination Therapy for Recurrent Pneumothorax in the Setting of Advanced Malignancy AID - 10.4187/respcare.03540 DP - 2014 Oct 21 TA - Respiratory Care PG - respcare.03540 4099 - http://rc.rcjournal.com/content/early/2014/10/21/respcare.03540.short 4100 - http://rc.rcjournal.com/content/early/2014/10/21/respcare.03540.full AB - The development of a persistent air leak after pneumothorax can be encountered in patients with underlying structural lung disease. In those with advanced malignancy or other comorbidities, the ability to tolerate general anesthesia and thoracoscopic procedures may limit definitive management. We describe the case of a 68-y-old male with refractory acute myelogenous leukemia presenting with recurrent secondary spontaneous pneumothorax and persistent air leak related to an underlying fungal pneumonia. Endobronchial valve placement allowed for timely chest tube removal and discharge from the hospital, as well as avoidance of a thoracoscopic procedure and pleurodesis.