RT Journal Article
SR Electronic
T1 Assessing New Technologies: Patient-Device Interactions and Deposition
JF Respiratory Care
FD American Association for Respiratory Care
SP 1151
OP 1160
VO 50
IS 9
A1 Smaldone, Gerald C
YR 2005
UL http://rc.rcjournal.com/content/50/9/1151.abstract
AB As our understanding of aerosol therapy matures, advances in technology afford the potential for solving the major problems in clinical aerosol delivery: control of variability in dosing, and targeting of therapy to different regions of the lung. As “interactive” devices are developed, testing on the bench becomes more sophisticated and demanding. The present review begins with simple in vitro testing techniques and addresses their ability to predict in vivo deposition. Advances in technology are reviewed and control of delivery in vivo is demonstrated.