TY - JOUR T1 - The Integrative Weaning Index in Elderly ICU Subjects JF - Respiratory Care SP - 333 LP - 339 DO - 10.4187/respcare.04524 VL - 62 IS - 3 AU - Leandro M Azeredo AU - Sérgio N Nemer AU - Carmen SV Barbas AU - Jefferson B Caldeira AU - Rosângela Noé AU - Bruno L Guimarães AU - Célia P Caldas Y1 - 2017/03/01 UR - http://rc.rcjournal.com/content/62/3/333.abstract N2 - BACKGROUND: With increasing life expectancy and ICU admission of elderly patients, mechanical ventilation, and weaning trials have increased worldwide.METHODS: We evaluated a cohort with 479 subjects in the ICU. Patients younger than 18 y, tracheostomized, or with neurologic diseases were excluded, resulting in 331 subjects. Subjects ≥70 y old were considered elderly, whereas those <70 y old were considered non-elderly. Besides the conventional weaning indexes, we evaluated the performance of the integrative weaning index (IWI). The probability of successful weaning was investigated using relative risk and logistic regression. The Hosmer-Lemeshow goodness-of-fit test was used to calibrate and the C statistic was calculated to evaluate the association between predicted probabilities and observed proportions in the logistic regression model.RESULTS: Prevalence of successful weaning in the sample was 83.7%. There was no difference in mortality between elderly and non-elderly subjects (P = .16), in days of mechanical ventilation (P = .22) and days of weaning (P = .55). In elderly subjects, the IWI was the only respiratory variable associated with mechanical ventilation weaning in this population (P < .001).CONCLUSIONS: The IWI was the independent variable found in weaning of elderly subjects that may contribute to the critical moment of this population in intensive care. ER -