TY - JOUR T1 - Reference Values for the 6-min Walk Distance (6MWT) in Healthy Children Aged 7 to 12 Years in Brazil: Main Results of the TC6minBRASIL Multi-Center Study JF - Respiratory Care DO - 10.4187/respcare.05686 SP - respcare.05686 AU - Lucas de Assis Pereira Cacau AU - Vitor Oliveira Carvalho AU - Alessandro dos Santos Pin AU - Carlos Raphael Araujo Daniel AU - Daisy Satomi Ykeda AU - Eliane Maria de Carvalho AU - Juliana Valente Francica AU - Luíza Martins Faria AU - Mansueto Gomes-Neto AU - Marcelo Fernandes AU - Marcelo Velloso AU - Marlus Karsten AU - Patrícia de Sá Barros AU - Valter Joviniano de Santana-Filho A2 - , Y1 - 2017/11/21 UR - http://rc.rcjournal.com/content/early/2017/11/21/respcare.05686.abstract N2 - INTRODUCTION: Brazil is a country with great climatic, socioeconomic, and cultural differences that does not yet have a reference value for the 6-min walk test (6MWT) in healthy children. To avoid misinterpretation, the use of equations to predict the maximum walking distance should be established in each country.OBJECTIVES: We sought to establish reference values and to develop an equation to predict the 6-min walk distance (6MWT) for healthy children in Brazil.METHODS: This is a cross-sectional multi-center study that included 1,496 healthy children, aged 7 to 12 y, assessed across 11 research sites in all regions of Brazil, and recruited from public and private schools in their respective regions. Each child was assessed for weight and height. Walking distance was our main outcome. An open-source software environment for statistical computing was used for statistical analysis.RESULTS: We observed a higher average distance walked by boys (531.1 m) than by girls (506.2 m), with a difference of 24.9 m (P < .001). We established 6MWT reference values for boys with the following equation: Distance = (16.86 × age) + (1.89 × Δ heart rate) − (0.80 × weight) + (336.91 × R1) + (360.91 × R2). For girls the equation is as follows: Distance = (13.54 × age) + (1.62 × Δ heart rate) − (1.28 × weight) + (352.33 × R1) + (394.81 × R2).CONCLUSION: Reference values were established for the 6MWT in healthy children aged 7–12 y in Brazil. ER -