RT Journal Article SR Electronic T1 Inspiratory Capacity and Vital Capacity of Healthy Subjects 9–81 Years of Age at Moderate-High Altitude JF Respiratory Care FD American Association for Respiratory Care SP respcare.06284 DO 10.4187/respcare.06284 A1 Silvia Cid-Juárez A1 Ireri Thirión-Romero A1 Luis Torre-Bouscoulet A1 Laura Gochicoa-Rangel A1 David Martínez-Briseño A1 Iván Y Hernández-Paniagua A1 Olivia Delgadillo-Ruiz A1 Selene Guerrero-Zúñiga A1 Rodrigo Del Río-Hidalgo A1 Daniel Cortés-Medina A1 Peter E Bapo-López A1 Pablo León-Gómez A1 Anaid Bautista-Bernal A1 Rogelio Pérez-Padilla YR 2019 UL http://rc.rcjournal.com/content/early/2019/01/15/respcare.06284.abstract AB BACKGROUND: Measurements of inspiratory capacity (IC) and vital capacity (VC) are used to recognize dynamic hyperinflation, but appropriate reference values are required to achieve accurate clinical interpretations. Altitude above sea level is a potential determining factor for lung volumes, including IC and VC.OBJECTIVE: To describe IC and VC for healthy people who live in Mexico City at an altitude of 2,240 m above sea level.METHODS: Healthy subjects ages 9–81 y completed slow spirometry by following 2005 American Thoracic Society/European Respiratory Society standards. Once associations were explored, linear regression models were constructed and values were compared with those from previously published equations.RESULTS: A total of 441 healthy subjects (55.1% women) participated. The mean age was 32 y (minimum age, 9 y; maximum age, 81 y). IC and VC measurements were associated with sex, age, height, and weight. An accelerated increase in IC and VC was evident from 9 to 20 y of age, followed by a gradual decrease in both sexes. In general, IC was higher in our population than predicted by previously published reference equations.CONCLUSION: IC in healthy people at 2,240 m above sea level was higher than that of previous reports about European and Latin-American subjects of the same height, sex, and age who were at sea level. The present study provided robust reference values for persons who lived at a moderate altitude.