TY - JOUR T1 - Oxygen Consumption in Two Portable Ventilators Using a High Pressure Gas Source JF - Respiratory Care VL - 64 IS - Suppl 10 SP - 3236318 AU - Justin Scott Phillips AU - Lance Pingul Pangilinan AU - Edward Karim Saliba AU - Mark Satomi Siobal AU - Edna Lee Warnecke Y1 - 2019/10/01 UR - http://rc.rcjournal.com/content/64/Suppl_10/3236318.abstract N2 - Background: The VOCSN (Ventec Life Systems, Bothell, WA) and Trilogy (Philips Respironics, Murrysville, PA) ventilators can deliver oxygen via low or high pressure sources utilizing different circuits. We evaluated and compared oxygen consumption from a high pressure gas source using the two ventilators with a null hypothesis that there would be no difference. Methods: The VOCSN and Trilogy ventilators were evaluated using a high pressure gas source (e-cylinders regulated to 50 psi) with both passive (constant leak) and active (exhalation valve) circuits connected to a TTL test lung (Michigan Instruments, Grand Rapids, MI). The three simulated TTL lung models were: normal - Cst 60 mL/cm H2O and Raw 5 cm H2O/L/s, restrictive - Cst 30 mL/cm H2O and Raw 5 cm H2O/L/s, and obstructive - Cst 60 mL/cm H2O, Raw 20 cm H2O/L/s. Using pressure ventilation modes, the peak pressure and rise time were titrated to achieve a tidal volume of 500 mL, as measured by a Certifier FA Plus (TSI Inc, Shoreview MN). Other settings include: frequency 12 breaths/min, PEEP 5 cm H2O and IT 1.0 second, set FIO2 of 0.40. Delivered FIO2 was measured by the Handi + oxygen analyzer (Maxtec, Salt Lake City, UT) at the lung inlet. In addition, the VOCSN pulse dose function was evaluated by titrating its oxygen flow to achieve an FIO2 of approximately 0.40. We measured the length of time to reduce e-cylinder pressure by 100 PSI for each lung model and test configuration, then calculated the liters of oxygen utilized per minute during each test run. A series of three tests were performed for all lung models and circuit configurations. Data for the three lung models were averaged for each test configuration and reported as the mean ± SD for both circuits. Results: Tidal volume delivery and measured FIO2 remained relatively constant during all lung models, test configurations and circuit types (501 ± 7 mL and 0.397 ± 0.01 respectively). Oxygen consumption using VOCSN with pulse dose oxygen delivery was 1.7 ± 0.7 and 1.7 ± 0.1 L/min, using VOCSN with set FIO2 was 4.8 ± 0.8 and 2.4 ± 0.1 L/min, and using Trilogy with set FIO2 was 5.2 ± 1.0 and 4.8 ± 0.9 L/min with passive and active circuits respectively. Conclusions: Oxygen utilization was lowest using the VOCSN ventilator with pulse dose oxygen delivery with both the passive and active circuits, and with VOCSN using a set FIO2 with the active circuit compared to the Trilogy 202 ventilator. ER -