@article {Shan1087, author = {Jun Shan and Hong-Lin Chen and Jian-Hua Zhu}, title = {Diagnostic Accuracy of Clinical Pulmonary Infection Score for Ventilator-Associated Pneumonia: A Meta-analysis}, volume = {56}, number = {8}, pages = {1087--1094}, year = {2011}, doi = {10.4187/respcare.01097}, publisher = {Respiratory Care}, abstract = {OBJECTIVE: To assess the diagnostic accuracy of the clinical pulmonary infection score in the diagnosis of ventilator-associated pneumonia in mechanically ventilated patients. METHODS: We searched PubMed and the Cochrane database, and included only studies that compared clinical pulmonary infection score with quantitative microbiological analysis of samples for diagnosing ventilator-associated pneumonia. We constructed 2-by-2 tables of diagnostic accuracy from each article, and meta-analyzed the results by pooling estimates of sensitivity, specificity, likelihood ratio for positive index test, likelihood ratio for negative index test, diagnostic odds ratio, and 95\% confidence intervals. RESULTS: Thirteen studies met the inclusion criteria. The pooled estimates for sensitivity and specificity for clinical pulmonary infection score were 65\% (95\% CI 61{\textendash}69\%) and 64\% (95\% CI 60{\textendash}67\%), respectively. The combined diagnostic odds ratio was 4.85 (95\% CI 2.42{\textendash}9.71) and the area under the curve was 0.748 (95\% CI 0.65{\textendash}0.85). CONCLUSIONS: The diagnostic performance of the clinical pulmonary infection score for ventilator-associated pneumonia is moderate. However, the clinical pulmonary infection score is simple and easy to perform, and may still be useful in diagnosing ventilator-associated pneumonia.}, issn = {0020-1324}, URL = {https://rc.rcjournal.com/content/56/8/1087}, eprint = {https://rc.rcjournal.com/content/56/8/1087.full.pdf}, journal = {Respiratory Care} }