RT Journal Article
SR Electronic
T1 Diffuse Cystic Lung Diseases
JF Respiratory Care
FD American Association for Respiratory Care
SP 111
OP 126
DO 10.4187/respcare.07117
VO 65
IS 1
A1 Baha Obaidat
A1 Dina Yazdani
A1 Kathryn A Wikenheiser-Brokamp
A1 Nishant Gupta
YR 2020
UL http://rc.rcjournal.com/content/65/1/111.abstract
AB Diffuse cystic lung diseases (DCLDs) are a group of diverse pulmonary disorders with varying pathophysiology that are characterized by the presence of thin-walled, air-filled spaces within lung parenchyma. High-resolution computed tomography plays a crucial role in the evaluation of DCLDs, and cyst characteristics such as morphology, distribution, and the presence of other associated radiologic findings can help distinguish between different DCLDs. DCLDs can be classified according to their underlying pathophysiology as neoplastic, genetic, lymphoproliferative, infectious, associated with other forms of interstitial lung disease, or related to smoking. In this review we will provide a clinical overview on the most common DCLDs that are encountered in clinical practice: lymphangioleiomyomatosis, pulmonary Langerhans cell histiocytosis, Birt-Hogg-Dubé syndrome, and lymphoid interstitial pneumonia/follicular bronchiolitis, with a focus on practical aspects that can help clinicians in the optimal diagnosis and management of patients with DCLDs.