RT Journal Article SR Electronic T1 Vibration-Response Imaging Versus Quantitative Perfusion Scintigraphy in the Selection of Patients for Lung-Resection Surgery JF Respiratory Care FD American Association for Respiratory Care SP 1936 OP 1941 VO 56 IS 12 A1 Fatma Comce A1 Zuleyha Bingol A1 Esen Kiyan A1 Serhan Tanju A1 Alper Toker A1 Pembe Cagatay A1 Turhan Ece YR 2011 UL http://rc.rcjournal.com/content/56/12/1936.abstract AB BACKGROUND: In patients being considered for lung-resection surgery, quantitative perfusion scintigraphy is used to predict postoperative lung function and guide the determination of lung-resection candidacy. Vibration-response imaging has been proposed as a noninvasive, radiation-free, and simpler method to predict postoperative lung function. We compared vibration-response imaging to quantitative perfusion scintigraphy for predicting postoperative FEV1 and diffusing capacity of the lung for carbon monoxide (DLCO). METHODS: We enrolled 35 candidates for lung resection. Twenty-five patients had preoperative FEV1 and DLCO measurements. RESULTS: The vibration-response-imaging measurements showed strong correlation with the quantitative-perfusion-scintigraphy measurements of predicted postoperative FEV1% (r = 0.87, P < .001), predicted postoperative FEV1 (r = 0.90, P < .001), and predicted postoperative DLCO% (r = 0.90, P < .001). There was a correlation between predicted postoperative FEV1 (% and L) measured via quantitative perfusion scintigraphy and the actual postoperative FEV1 (% and L) (r = 0.47, P = .048, r = 0.73, P < .001). There was no difference between the vibration-response-imaging measurements and the actual postoperative measurements of predicted postoperative FEV1 (% and L). There was a correlation between predicted postoperative FEV1 (% and L) measured via vibration-response imaging and actual postoperative FEV1 (% and L) (r = 0.52, P = .044, r = 0.79, P < .001). The mean differences between the predicted and actual postoperative FEV1 values were 49 mL with vibration-response imaging, versus 230 mL with quantitative perfusion scintigraphy. Neither the vibration-response imaging nor the quantitative perfusion scintigraphy predicted postoperative DLCO% values agreed with the actual postoperative DLCO% values. CONCLUSIONS: Vibration-response imaging may be a good alternative to quantitative perfusion scintigraphy in evaluating lung-resection candidacy.