PT - JOURNAL ARTICLE AU - Morgan Nichole Meyers AU - Arzu Ari AU - Punkaj Gupta TI - Is It Safe to Use Intrapulmonary Percussive Ventilation on Post-Operative Neonates With Cardiovascular Surgery? DP - 2020 Oct 01 TA - Respiratory Care PG - 3444414 VI - 65 IP - Suppl 10 4099 - http://rc.rcjournal.com/content/65/Suppl_10/3444414.short 4100 - http://rc.rcjournal.com/content/65/Suppl_10/3444414.full AB - Background: The risk of developing atelectasis, lung derecruitment, and lung inflammation following postoperative cardiac surgery is heightened. These complications are not only associated with increasing financial cost but also with increase hospital length of stay, which is amplified in children with heart disease. The purpose of this study is to determine the safety of intrapulmonary percussive ventilation (IPV) in postoperative neonates with cardiovascular surgery. Methods: After obtaining the IRB approval and informed consent from the parents, 10 patients were enrolled in this pilot study. They were postoperatively mechanically ventilated patients with both single ventricle and two-ventricle physiology and receiving pulmonary clearance via the IPV (Percussionaire) within the first 4 days of congenital heart surgery. Patients who required extracorporeal membrane oxygenation (ECMO) and patients with obstructive sleep apnea, macroglossia, difficult airway, increased intracranial pressure, increased intraocular pressure, or those weighing less than 2.0 kg were excluded. Heart rate (HR), systolic and diastolic blood pressure (SBP and DBP, respectively), mean airway pressure (MAP), oxygen saturation (SpO2), bleeding from the endotracheal tube, and/or any other unanticipated complications were noted. Information was collected from the monitoring system 10 minutes, 5 minutes, 2 minutes, 1 minute before IPV followed by a 10 minute IPV treatment. Data was then collected 1 minute, 2 minutes, 5 minutes, and 10 minutes after IPV. Data was collected from each patient one time within a 24-hour period, following surgery. Descriptive statistics and the dependent t-test was used for data analysis (P-value<0.05). Results: Table below shows means (± standard deviations) measured 5 minutes pre- and post- IPV on post-operative cardiovascular pediatrics. 60% of subjects were male while the remaining 40% of the study population was female with patients ranging from 1 to 4 months with a median age of 1.5 months. Comparisons of the pre- and post-IPV variables showed no significant difference in HR (P= 0.196), SBP (P= 0.370), DBP (P= 0.894), MAP (P=0.905), and SpO2 (P= 0.220). No bleeding from the endotracheal tube occurred in this study. There were no unanticipated complications that occurred in this study. Conclusions: The use of IPV in postoperative neonates with cardiovascular surgery is a safe practice because it did not cause any unanticipated complications and impact the patient’s vital signs, MAP and SpO2. View this table: