TY - JOUR T1 - Six-Week Inspiratory Muscle Training Combined With Exercise in Patients Undergoing Video-Assisted Thoracoscopic Surgery: A Randomized Controlled Trial JF - Respiratory Care VL - 65 IS - Suppl 10 SP - 3449487 AU - Jui-Fang Liu AU - ching-wan Tseng AU - Nai-Ying Kuo Y1 - 2020/10/01 UR - http://rc.rcjournal.com/content/65/Suppl_10/3449487.abstract N2 - Background: Little is known about the effect of combining exercise with respiratory muscle training on the recovery of muscle strength and postoperative pulmonary complications after video-assisted thoracoscopic surgery (VATS). We conducted a randomized clinical trial exploring the benefits of inspiratory muscle training combined with exercise on the recovery of inspiratory and skeletal muscles strength and PPCs after VATS for lung cancer patients. Methods: 54 patients undergoing VATS for lung cancer resection were recruited and assigned to a training group (n = 26) and a control group (n = 28). Patients in the training group received threshold inspiratory training, incentive spirometer training, and aerobic exercise training for 6 weeks. At the 2nd week, 6th week, and 12th week, the patients were assessed for the primary outcome of inspiratory muscle strength and lung expansion volume, and 6-min walk test, and the secondary outcome of the incidence of PPCs. Results: The training group showed significant improvement of maximum inspiratory pressure at the 6th week (P = 0.018), and maximum expiratory pressure at the 2nd week (P = 0.015) and 12th week (P = 0.012). The lung expansion volume of the training group improved significantly at the 2nd week (1P = 0.020), 6th week (P =0.006), and 12th week (P < 0.001). The patients in the training group showed significant improvement of 6-min walking distance at the 2nd week (P = 0.002), 6th week (P = 0.007), and 12th week (P = 0.036). The incidence of PPCs was similar. Conclusions: This is the first randomized clinical trial, patients who underwent VATS showed significant improvement of inspiratory muscle strength measured by maximum inspiratory pressure and maximum expiratory pressure, lung expansion volume, and 6-min walk distance with 6 weeks of combined inspiratory muscle training and aerobic exercise. ER -