PT - JOURNAL ARTICLE AU - Steven M Donn AU - Win Boon TI - Mechanical Ventilation of the Neonate: Should We Target Volume or Pressure? DP - 2009 Sep 01 TA - Respiratory Care PG - 1236--1243 VI - 54 IP - 9 4099 - http://rc.rcjournal.com/content/54/9/1236.short 4100 - http://rc.rcjournal.com/content/54/9/1236.full AB - For more than 40 years conventional mechanical ventilation has been used for the treatment of neonatal respiratory failure. Until relatively recently, this was accomplished with time-cycled pressure-limited ventilation, using intermittent mandatory ventilation. Earlier attempts at volume-targeted ventilation were largely ineffective because of technological limitations. The advent of microprocessor-based devices gives the clinician an option to choose either target variable to treat neonatal patients. This paper reviews the principles of each and the accumulated evidence.