RT Journal Article SR Electronic T1 Mechanical Ventilation of the Neonate: Should We Target Volume or Pressure? JF Respiratory Care FD American Association for Respiratory Care SP 1236 OP 1243 VO 54 IS 9 A1 Steven M Donn A1 Win Boon YR 2009 UL http://rc.rcjournal.com/content/54/9/1236.abstract AB For more than 40 years conventional mechanical ventilation has been used for the treatment of neonatal respiratory failure. Until relatively recently, this was accomplished with time-cycled pressure-limited ventilation, using intermittent mandatory ventilation. Earlier attempts at volume-targeted ventilation were largely ineffective because of technological limitations. The advent of microprocessor-based devices gives the clinician an option to choose either target variable to treat neonatal patients. This paper reviews the principles of each and the accumulated evidence.