RT Journal Article SR Electronic T1 Humidification and Secretion Volume in Mechanically Ventilated Patients JF Respiratory Care FD American Association for Respiratory Care SP 1329 OP 1335 VO 54 IS 10 A1 Mario Solomita A1 Lucy B Palmer A1 Feroza Daroowalla A1 Jeffrey Liu A1 Dori Miller A1 Deniese S LeBlanc A1 Gerald C Smaldone YR 2009 UL http://rc.rcjournal.com/content/54/10/1329.abstract AB OBJECTIVE: To determine potential effects of humidification on the volume of airway secretions in mechanically ventilated patients. METHODS: Water vapor delivery from devices providing non-heated-wire humidification, heated-wire humidification, and heat and moisture exchanger (HME) were quantified on the bench. Then, patients requiring 24-hour mechanical ventilation were exposed sequentially to each of these humidification devices, and secretions were removed and measured by suctioning every hour during the last 4 hours of the 24-hour study period. RESULTS: In vitro water vapor delivery was greater using non-heated-wire humidification, compared to heated-wire humidification and HME. In vivo, a total of 9 patients were studied. Secretion volume following humidification by non-heated-wire humidification was significantly greater than for heated-wire humidification and HME (P = .004). CONCLUSIONS: The volume of secretions appeared to be linked to humidification, as greater water vapor delivery measured in vitro was associated with greater secretion volume in vivo.