PT  - JOURNAL ARTICLE
AU  - Mohari, Nivedita
AU  - Raj, Dinesh
AU  - Lodha, Rakesh
AU  - Kabra, Sushil K
TI  - Prolonged High-Frequency Oscillatory Ventilation in Tubercular Multifocal Cystic Lung Disease
AID  - 10.4187/respcare.01749
DP  - 2012 Dec 01
TA  - Respiratory Care
PG  - 2111--2114
VI  - 57
IP  - 12
4099  - http://rc.rcjournal.com/content/57/12/2111.short
4100  - http://rc.rcjournal.com/content/57/12/2111.full
AB  - Multifocal cystic lung disease in infants is most commonly congenital, and is managed surgically with perioperative mechanical ventilation. Multifocal cystic lung disease in infants may be due to tuberculosis. We report a young infant with tubercular multifocal cystic lung disease and respiratory failure. The initial chest imaging revealed diffuse nodular infiltrates. Soon after admission he required conventional mechanical ventilation for respiratory failure. The bronchoalveolar lavage fluid grew Mycobacterium tuberculosis in culture. Subsequent chest imaging showed progression to multifocal cystic lung disease. The ventilation mode was changed to high-frequency oscillatory ventilation (HFOV) due to persistent CO2 retention in the presence of cystic lung disease. The cystic lung disease reversed with antitubercular treatment and prolonged HFOV with slow wean.