PT  - JOURNAL ARTICLE
AU  - Wen-I Liao
AU  - Shih-Hung Tsai
AU  - Sheng-Kang Chiu
TI  - Successful Use of Extracorporeal Membrane Oxygenation in a Hematopoietic Stem Cell Transplant Patient With Idiopathic Pneumonia Syndrome
AID  - 10.4187/respcare.01716
DP  - 2013 Feb 01
TA  - Respiratory Care
PG  - e6--e10
VI  - 58
IP  - 2
4099  - http://rc.rcjournal.com/content/58/2/e6.short
4100  - http://rc.rcjournal.com/content/58/2/e6.full
AB  - We report the case of an adult patient with idiopathic pneumonia syndrome following allogeneic hematopoietic stem cell transplantation, which was successfully managed with venovenous extracorporeal membrane oxygenation (ECMO) and immunosuppressive therapy. A 30-year-old man with precursor B cell acute lymphocytic leukemia had received chemotherapy 10 years previously, with complete remission. He underwent allogeneic hematopoietic stem cell transplantation 4 months prior to enrollment, owing to leukemia relapse. One hundred thirty days post-transplant the patient developed shortness of breath, nonproductive cough, and low-grade fever for 1 week. He subsequently developed acute hypercapnic and hypoxic respiratory failure that was unresponsive to conventional medical therapy. He was successfully managed with venovenous ECMO for 19 days, with complete resolution of his respiratory symptoms. Thus, judicious use of ECMO as a bridge before steroid and other conventional therapy take effect in patients with isolated respiratory failure appears justified.