PT - JOURNAL ARTICLE AU - Hickey, Andrew J AU - Cummings, Matthew J AU - Short, Briana AU - Brodie, Daniel AU - Panzer, Oliver AU - Madahar, Purnema AU - O'Donnell, Max R TI - Approach to the Physiologically Challenging Endotracheal Intubation in the Intensive Care Unit AID - 10.4187/respcare.10821 DP - 2023 Oct 01 TA - Respiratory Care PG - 1438--1448 VI - 68 IP - 10 4099 - http://rc.rcjournal.com/content/68/10/1438.short 4100 - http://rc.rcjournal.com/content/68/10/1438.full AB - Endotracheal intubation for airway management is a common procedure in the ICU. Intubation may be difficult due to anatomic airway abnormalities but also due to physiologic derangements that predispose patients to cardiovascular collapse during the procedure. Results of studies demonstrate a high incidence of morbidity and mortality associated with airway management in the ICU. To reduce the likelihood of complications, medical teams must be well versed in the general principles of intubation and be prepared to manage physiologic derangements while securing the airway. In this review, we present relevant literature on the approach to endotracheal intubation in the ICU and provide pragmatic recommendations relevant to medical teams performing intubations in patients who are physiologically unstable.