RT Journal Article
SR Electronic
T1 Benign Metastasizing Leiomyoma Presenting as Cavitating Lung Nodules
JF Respiratory Care
FD American Association for Respiratory Care
SP e94
OP e97
DO 10.4187/respcare.02775
VO 59
IS 7
A1 Angeliki A Loukeri
A1 Ioannis N Pantazopoulos
A1 Rodoula Tringidou
A1 Pantelis Giampoudakis
A1 Argyro Valaskatzi
A1 Pinelopi A Loukeri
A1 Christos F Kampolis
YR 2014
UL http://rc.rcjournal.com/content/59/7/e94.abstract
AB Benign metastasizing leiomyoma (BML) was initially used to describe single or multiple pulmonary nodules composed of proliferating smooth muscle cells (lacking cellular atypia) in premenopausal females 3 months to 20 y after hysterectomy for uterine leiomyoma. The lung is the most commonly involved site, thus including many malignant and benign entities in the differential diagnosis. The present case refers to a 47-y-old premenopausal woman with a history of subtotal hysterectomy for a uterine leiomyoma presenting with bilateral cavitating pulmonary nodules. A number of nodules were resected by video-assisted thoracoscopic surgery. The histological findings in correlation with the immunohistochemical results were consistent with the diagnosis of BML. A bilateral salpingo-oophorectomy was performed, combined with complete removal of the remaining cervix. One year later, the subject remains asymptomatic, and the pulmonary nodules are stable with regard to number, size, location, and morphology.