RT Journal Article
SR Electronic
T1 Respiratory Therapist-Driven Mechanical Ventilation Protocol Is Associated With Increased Lung Protective Ventilation
JF Respiratory Care
FD American Association for Respiratory Care
SP 1071
OP 1080
DO 10.4187/respcare.11599
VO 69
IS 9
A1 Berg, Alaina C
A1 Evans, Erin
A1 Okoro, Uche E
A1 Pham, Vivian
A1 Foley, Tyler M
A1 Hlas, Chloe
A1 Kuhn, Justin D
A1 Nassar, Boulos
A1 Fuller, Brian M
A1 Mohr, Nicholas M
YR 2024
UL http://rc.rcjournal.com/content/69/9/1071.abstract
AB BACKGROUND: Mechanical ventilation is a common life-saving procedure but can lead to serious complications, including ARDS and oxygen toxicity. Nonadherence to lung-protective ventilation guidelines is common. We hypothesized that a respiratory therapist–driven mechanical ventilation bundle could increase adherence to lung-protective ventilation and decrease the incidence of pulmonary complications in the ICU.METHODS: A respiratory therapist–driven protocol was implemented on August 1, 2018, in all adult ICUs of a Midwestern academic tertiary center. The protocol targeted low tidal volume, adequate PEEP, limiting oxygen, adequate breathing frequency, and head of the bed elevation. Adherence to lung-protective guidelines and clinical outcomes were retrospectively observed in adult subjects admitted to the ICU and on ventilation for ≥ 24 h between January 2011 and December 2019.RESULTS: We included 666 subjects; 68.5% were in the pre-intervention group and 31.5% were in the post-intervention group. After adjusting for body mass index and intubation indication, a significant increase in overall adherence to lung-protective ventilation guidelines was observed in the post-intervention period (adjusted odds ratio 2.48, 95% CI 1.73–3.56). Fewer subjects were diagnosed with ARDS in the post-intervention group (adjusted odds ratio 0.22, 95% CI 0.08–0.65) than in the pre-intervention group. There was no difference in the incidence of ventilator-associated pneumonia, ventilator-free days, ICU mortality, or death within 1 month of ICU discharge.CONCLUSIONS: A respiratory therapist–driven protocol increased adherence to lung-protective mechanical ventilation guidelines in the ICU and was associated with decreased ARDS incidence.