RT Journal Article SR Electronic T1 Current Advances and Gaps in Knowledge on Personalizing Masks for Noninvasive Respiratory Support JF Respiratory Care FD American Association for Respiratory Care SP 1201 OP 1211 DO 10.4187/respcare.11886 VO 69 IS 9 A1 Pigmans, Rosemijne R W P A1 Smith, Jonathan M A1 Markhorst, Dick G A1 van Woensel, Job B M A1 Dijkman, Coen D A1 Elphick, Heather E A1 Bem, Reinout A YR 2024 UL http://rc.rcjournal.com/content/69/9/1201.abstract AB Noninvasive respiratory support delivered through a face mask has become a cornerstone treatment for adults and children with acute or chronic respiratory failure. However, an imperfect mask fit by using commercially available interfaces is frequently encountered, which may result in patient discomfort and treatment inefficiency or failure. To overcome this challenge, over the past decade, increasing attention has been given to the development of personalized face masks, which are custom-made to address the specific facial dimensions of an individual patient. With this scoping review, we aim to provide a comprehensive overview of the current advances and gaps in knowledge with regard to the personalization masks for CPAP and NIV. We performed a systematic search of the literature and identified and summarized a total of 23 studies. Most studies included were involved in the development of nasal masks. Studies that targeted adult respiratory care mainly focused on chronic (home) ventilation and included some clinical testing in a relevant subject population. In contrast, pediatric studies focused mostly on respiratory support in the acute setting, whereas testing was limited to bench or case studies only. Most studies were positive with regard to the performance (ie, comfort, level of air leak, and mask pressure applied to the skin) of personalized masks in bench testing or in human, healthy or patient, subjects. Advances in the field of 3-dimensional scanning and soft material printing were identified, but important gaps in knowledge remain. In particular, more insight into cushion materials, headgear design, clinical feasibility, and cost-effectiveness is needed before definite recommendations can be made with regard to implementation of large-scale clinical programs that personalize noninvasive respiratory support masks for adults and children.