TY - JOUR T1 - Necrotizing Sarcoid Granulomatosis With an Uncommon Manifestation: Clinicopathological Features and Review of Literature JF - Respiratory Care SP - e132 LP - e136 DO - 10.4187/respcare.02842 VL - 59 IS - 9 AU - Chiara Giraudo AU - Nazarena Nannini AU - Elisabetta Balestro AU - Alessia Meneghin AU - Francesca Lunardi AU - Roberta Polverosi AU - Fiorella Calabrese Y1 - 2014/09/01 UR - http://rc.rcjournal.com/content/59/9/e132.abstract N2 - We report a rare case of an incidental diagnosis of necrotizing sarcoid granulomatosis (NSG) in a 60-y-old non-smoking male. The patient was admitted to the hospital for sudden back pain. Chest x-ray revealed areas of parenchymal consolidation and high-resolution computed tomography demonstrated a pulmonary nodular pattern with no lymph node enlargement. All laboratory and pulmonary function tests were normal. Bronchoscopy with bronchoalveolar lavage showed no sign of infection or specific inflammation. The diagnosis of NSG was made by histopathological examination of a surgical lung biopsy and by excluding other causes of granulomatous disease. In paucisymptomatic/asymptomatic patients, as in our case, therapy is not necessary, with a good prognosis and complete recovery. NSG is a rare systemic disease similar to sarcoidosis and Wegener's granulomatosis with a benign clinical course and should always be considered for patients with nodular pulmonary lesions even with subclinical or uncommon features. ER -