PT - JOURNAL ARTICLE AU - Jens Bräunlich AU - Hans-Jürgen Seyfarth AU - Armin Frille AU - Hubert Wirtz TI - Diffuse Interstitial Pulmonary Infiltrates in Malignant Melanoma AID - 10.4187/respcare.03621 DP - 2015 Jul 01 TA - Respiratory Care PG - e115--e117 VI - 60 IP - 7 4099 - http://rc.rcjournal.com/content/60/7/e115.short 4100 - http://rc.rcjournal.com/content/60/7/e115.full AB - Only a few cases of sarcoidosis-like reaction to a pharmacologic compound have been reported in patients with melanoma in the literature. Long-term treatment with interferon alpha may be assumed. We report a case of a 25-y-old man who presented to our department with diffuse interstitial pulmonary infiltrates and slightly enlarged mediastinal lymph nodes as determined by computed tomography. He had a history of malignant melanoma with 18 months of interferon alpha-2 therapy. Histological analysis of a transbronchial biopsy revealed sarcoidosis-like reactions.