PT  - JOURNAL ARTICLE
AU  - Yuki Sugiyama
AU  - Fumiko Shimizu
AU  - Sari Shimizu
AU  - Masatoshi Urasawa
AU  - Satoshi Tanaka
AU  - Mikito Kawamata
TI  - Severe Re-expansion Pulmonary Edema Induced by One-Lung Ventilation
AID  - 10.4187/respcare.03759
DP  - 2015 Aug 01
TA  - Respiratory Care
PG  - e134--e140
VI  - 60
IP  - 8
4099  - http://rc.rcjournal.com/content/60/8/e134.short
4100  - http://rc.rcjournal.com/content/60/8/e134.full
AB  - We present 2 cases of severe re-expansion pulmonary edema (RPE) after one-lung ventilation (OLV) for thoracic surgery. A 32-y-old woman with multiple lung metastases developed severe RPE after OLV during lung resection surgery. A 37-y-old man with infective endocarditis also developed severe RPE after OLV for mitral valve plasty with minimally invasive cardiac surgery. In both cases, results of a preoperative pulmonary function test and oxygenation were almost normal, and pleural effusion or pulmonary congestion was not detected in preoperative computed tomography; however, there was a possibility that subclinical lung injury existed before surgery. The levels of interleukin-8 and monocyte chemotactic protein-1, which are thought to play important roles in the development of lung injury, in bronchial secretions were extremely high after the onset of RPE. These results suggest that the pathogenesis of RPE shares, at least in part, a common pathophysiology of acute lung injury.