RT Journal Article
SR Electronic
T1 Severe Re-expansion Pulmonary Edema Induced by One-Lung Ventilation
JF Respiratory Care
FD American Association for Respiratory Care
SP e134
OP e140
DO 10.4187/respcare.03759
VO 60
IS 8
A1 Yuki Sugiyama
A1 Fumiko Shimizu
A1 Sari Shimizu
A1 Masatoshi Urasawa
A1 Satoshi Tanaka
A1 Mikito Kawamata
YR 2015
UL http://rc.rcjournal.com/content/60/8/e134.abstract
AB We present 2 cases of severe re-expansion pulmonary edema (RPE) after one-lung ventilation (OLV) for thoracic surgery. A 32-y-old woman with multiple lung metastases developed severe RPE after OLV during lung resection surgery. A 37-y-old man with infective endocarditis also developed severe RPE after OLV for mitral valve plasty with minimally invasive cardiac surgery. In both cases, results of a preoperative pulmonary function test and oxygenation were almost normal, and pleural effusion or pulmonary congestion was not detected in preoperative computed tomography; however, there was a possibility that subclinical lung injury existed before surgery. The levels of interleukin-8 and monocyte chemotactic protein-1, which are thought to play important roles in the development of lung injury, in bronchial secretions were extremely high after the onset of RPE. These results suggest that the pathogenesis of RPE shares, at least in part, a common pathophysiology of acute lung injury.