RT Journal Article SR Electronic T1 The Successful Management of a Patient With Exacerbation of Non-Cystic Fibrosis Bronchiectasis and Bilateral Fibrothorax Using a Venovenous Extracorporeal Carbon Dioxide Removal System JF Respiratory Care FD American Association for Respiratory Care SP e197 OP e200 DO 10.4187/respcare.03184 VO 59 IS 12 A1 Giovanna Arcaro A1 Andrea Vianello YR 2014 UL http://rc.rcjournal.com/content/59/12/e197.abstract AB Following unsuccessful treatment with noninvasive ventilation (NIV), patients requiring subsequent placement on invasive mechanical ventilation have a high mortality rate. Invasive mechanical ventilation is particularly problematic in patients with acute respiratory failure due to bronchiectasis exacerbation, as it is associated with a mortality rate of 19–35% and prolonged ICU stay. Here, we describe the successful management of a patient with exacerbated non-cystic fibrosis bronchiectasis using a pump-assisted venovenous system for extracorporeal CO2 removal (ProLUNG system) as an alternative to endotracheal intubation following NIV failure. The extracorporeal CO2 removal system proved to be safe and efficacious in this case study, and further studies focusing on its use in these types of cases seem warranted.