RT Journal Article SR Electronic T1 Ventilation-Induced Massive Lethal Air Embolism and Subcutaneous Emphysema in a Patient With a Lung Cavern JF Respiratory Care FD American Association for Respiratory Care SP e6 OP e10 DO 10.4187/respcare.03194 VO 60 IS 1 A1 Wim Verelst A1 Walter Verbrugghe A1 Martin Lammens A1 Annemie Snoeckx A1 Philippe G Jorens YR 2015 UL http://rc.rcjournal.com/content/60/1/e6.abstract AB The simultaneous occurrence of subcutaneous emphysema and intravascular air due to an air embolism is a rare condition. Here, we report a patient with COPD who developed a severe episode of hemoptysis due to rupture of a previously undiagnosed lung cavern. Intubation and ventilation led to the development of both massive subcutaneous emphysema and a massive air embolism, resulting from aspiration of air through a torn pulmonary vessel in the cavern. The dramatic amount of intravenous air and subsequent conduction along the venous system to the right heart and pulmonary trunk caused major hemodynamic compromise and ultimately death. The degree of subcutaneous emphysema, especially the massive venous air embolism, was unprecedented.