TY - JOUR T1 - Should High-Frequency Ventilation in the Adult Be Abandoned? JF - Respiratory Care SP - 791 LP - 800 DO - 10.4187/respcare.04584 VL - 61 IS - 6 AU - Albert P Nguyen AU - Ulrich H Schmidt AU - Neil R MacIntyre Y1 - 2016/06/01 UR - http://rc.rcjournal.com/content/61/6/791.abstract N2 - High-frequency oscillatory ventilation (HFOV) can improve ventilation-perfusion matching without excessive alveolar tidal stretching or collapse-reopening phenomenon. This is an attractive feature in the ventilation of patients with ARDS. However, two recent large multi-center trials of HFOV failed to show benefits in this patient population. The following review addresses whether, in view of these trails, HFOV should be abandoned in the adult population? ER -