PT - JOURNAL ARTICLE AU - Nguyen, Albert P AU - Schmidt, Ulrich H AU - MacIntyre, Neil R TI - Should High-Frequency Ventilation in the Adult Be Abandoned? AID - 10.4187/respcare.04584 DP - 2016 Jun 01 TA - Respiratory Care PG - 791--800 VI - 61 IP - 6 4099 - http://rc.rcjournal.com/content/61/6/791.short 4100 - http://rc.rcjournal.com/content/61/6/791.full AB - High-frequency oscillatory ventilation (HFOV) can improve ventilation-perfusion matching without excessive alveolar tidal stretching or collapse-reopening phenomenon. This is an attractive feature in the ventilation of patients with ARDS. However, two recent large multi-center trials of HFOV failed to show benefits in this patient population. The following review addresses whether, in view of these trails, HFOV should be abandoned in the adult population?