RT Journal Article SR Electronic T1 Should High-Frequency Ventilation in the Adult Be Abandoned? JF Respiratory Care FD American Association for Respiratory Care SP 791 OP 800 DO 10.4187/respcare.04584 VO 61 IS 6 A1 Nguyen, Albert P A1 Schmidt, Ulrich H A1 MacIntyre, Neil R YR 2016 UL http://rc.rcjournal.com/content/61/6/791.abstract AB High-frequency oscillatory ventilation (HFOV) can improve ventilation-perfusion matching without excessive alveolar tidal stretching or collapse-reopening phenomenon. This is an attractive feature in the ventilation of patients with ARDS. However, two recent large multi-center trials of HFOV failed to show benefits in this patient population. The following review addresses whether, in view of these trails, HFOV should be abandoned in the adult population?