RT Journal Article
SR Electronic
T1 Severe Acute Respiratory Failure Secondary to Acute Fibrinous and Organizing Pneumonia Requiring Mechanical Ventilation: A Case Report and Literature Review
JF Respiratory Care
FD American Association for Respiratory Care
SP 1337
OP 1341
DO 10.4187/respcare.01452
VO 57
IS 8
A1 López-Cuenca, Sonia
A1 Morales-García, Silvia
A1 Martín-Hita, Ana
A1 Frutos-Vivar, Fernando
A1 Fernández-Segoviano, Pilar
A1 Esteban, Andrés
YR 2012
UL http://rc.rcjournal.com/content/57/8/1337.abstract
AB A 27-year-old woman was admitted to our ICU with acute hypoxemic respiratory failure and criteria for ARDS. Despite an FIO2 of 1.0 and a lung protective strategy, the patient died on day 15 without any improvement. The relatives gave consent for post-mortem analysis. The histopathologic study of the lung showed findings typical of an acute fibrinous and organizing pneumonia. Apropos of this case we performed a PubMed search. We found 13 articles, including a total of 29 patients. Acute fibrinous and organizing pneumonia is an unusual cause of acute lung injury. The diagnostic criterion is histopathologic. There is little information regarding the pathophysiology of this illness. Important questions remain regarding this disease, including predisposing factors and management. Patients who require mechanical ventilation have poor outcomes.