Clinical studyContaminated medication nebulizers in mechanical ventilator circuits: Source of bacterial aerosols☆
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Cited by (139)
Ventilator circuit leak alarm–think of unusual cause
2019, Trends in Anaesthesia and Critical CareClinical outcome associated with the use of different inhalation method with and without humidification in asthmatic mechanically ventilated patients
2017, Pulmonary Pharmacology and TherapeuticsCitation Excerpt :When used with optimal technique, MDIs and nebulizers were found to be equally effective in the management of mechanically ventilated patients with different obstructive lung disease [48]. For routine bronchodilator therapy, MDIs may be preferred because of their convenience, more consistent dosing, and, similar to VMN, potential reduced risk of bacterial contamination when compared to JN [49,50]. In one survey of neonatal ICUs, MDI use was reported to have increased significantly over a period of approximately 20 years [51].
Fill volume, humidification and heat effects on aerosol delivery and fugitive emissions during noninvasive ventilation
2017, Journal of Drug Delivery Science and TechnologyCitation Excerpt :In our model the use of humidification (HN) increased residual volume in the JN medication reservoir compared to NN (p = 0.048). This might be due to the location of the JN medication reservoir below the T-piece in the circuit which encourages return of aerosol droplets condensate to the reservoir allowing it to be either re-nebulized or left in the reservoir, which could lead to contaminated aerosol delivery to the patient [2,4,16,22]. However, there was no effect at all by the humidification or heat on the amount of salbutamol left in the medication reservoir of VMN.
High flow, humidified-reheated oxygen therapy: A new oxygenation techniquefor adults
2013, Revue des Maladies RespiratoiresInhalation therapy: Provocation tests, infectious risks, acute bronchiolitis and ENT diseases. GAT aerosolstorming, Paris 2011
2012, Revue des Maladies Respiratoires
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This work was supported by a Program Project Grant, Blue Cross-Blue Shield, Massachusetts Hospital Association, Boston, Massachusetts, and was presented in part at the 23rd Interscience Conference on Antimicrobial Agents in Chemotherapy, October 21, 1983, Las Vegas, Nevada, and the 10th Annual Meeting of the Association for Practitioners in Infection Control, May 14, 1983, San Diego, California.
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From the Divisions of Infectious Diseases and Pulmonary Medicine, Department of Medicine, Boston University School of Medicine, Boston City Hospital, Boston, Massachusetts.