Original articleUtility of C-reactive protein measurements for empyema diagnosis after pneumonectomy
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α-1-Acid glycoprotein as a biomarker for the early diagnosis and monitoring the prognosis of sepsis
2015, Journal of Critical CareCitation Excerpt :Costello et al [40]reported that AGP can also inhibit platelet aggregation induced by adenosine diphosphate and adrenaline. Infection persistence may present with either a markedly sustained elevation in the levels of inflammation or a secondary rise in these levels [41]. In our study, the patients who died had persistent critical infection by surveillance results of pathogen, and the serum AGP levels, WBC counts, and SOFA scores of the nonsurvivors were remarkably higher than those of the survivors at the 5 time points (days 1, 3, 5, 7, and 10).
C-reactive protein and lung diseases
2014, International Journal of Biochemistry and Cell BiologyAn evaluation of clinical stability criteria to predict hospital course in community-acquired pneumonia
2013, Clinical Microbiology and InfectionCitation Excerpt :We confirmed that a reduction in CRP was associated with a low mortality and need for MV/VS. Interestingly, CRP was the most accurate marker at predicting development of complicated pneumonia. We have previously found that a low CRP on admission was associated with a low risk of complicated parapneumonic effusion or empyema [25] and the association between a persistently raised CRP and the development of empyema has been long recognized [26]. This study suggests that adding C-reactive protein to the Halms criteria improved the AUC for predicting adverse outcomes but the difference was only statistically significant for prediction of complicated pneumonia.
Chest tube tip culture as a predictor of postoperative infection in lung cancer operations
2013, Annals of Thoracic SurgeryCitation Excerpt :A similar mechanism was suggested in general thoracic surgery; that is, chest tube tip culture may detect the early phase of postoperative empyema. Some reports showed that C-reactive protein, procalcitonin, or perioperative microbiologic monitoring of tracheal aspirates are good predictors of postoperative infections in patients who have undergone lung resection [7, 20, 21]. Although this study did not analyze the relationship between chest tube tip culture and other laboratory variables, considering that infection occurred 4 ± 3 days after chest tube removal in this study, positive chest tube tip culture in combination with these variables and subtle clinical findings in this period may predict postoperative infection, and treatment before the clinical findings of infection become severe may then be possible.
Does bilobectomy offer satisfactory long-term survival outcome for non-small cell lung cancer?
2013, Annals of Thoracic SurgeryCitation Excerpt :Chest X-rays were performed daily until chest drain removal and prior to hospital discharge. Serial C-reactive protein levels were routinely measured every 3 days for early detection of infection such as empyema [11]. In order to reduce the residual pleural space cavity, patients received active respiratory physiotherapy twice daily, associated with optimizing bronchodilator therapy.
A new method for detection of post-pneumonectomy broncho-pleural fistulas
2003, Annals of Thoracic SurgeryCitation Excerpt :Conversely, it is well known that empyema is not necessarily accompanied by a BPF [1]. Although in most cases diagnosis of empyema with BPF is evident on the basis of clinical, laboratory, and endoscopic findings [1, 6], in some instances diagnosis remains in question despite repeated invasive studies [1, 4], mainly repeated fiberoptic bronchoscopies. In patients with an established diagnosis of postpneumonectomy empyema, a BPF should be accurately searched for, in order to optimally treat these patients [1, 4].