Narrow-band imaging system with magnifying endoscopy for superficial esophageal lesions☆
Section snippets
Patients
A total of 41 consecutive patients (37 men, 4 women; mean age 63.5 [7.3] years) were enrolled in the study between March 2002 and January 2003. There were 18 patients with superficial esophageal squamous cell carcinoma, 8 with dysplasia, two with esophagitis, and 13 with normal mucosa. All patients with superficial esophageal cancer were treated by EMR, and all resected specimens were retrieved for histopathologic evaluation. Depth of invasion was classified according to the esophageal cancer
Results
Magnifying endoscopic images with the standard videoendoscopic system and NBI system were obtained in all cases; no complication was encountered.
Representative pairs of regular and NBI images are shown in Figure 4. In the regular images, IPCL appear as reddish lines, and the background mucosa is light orange in color. In NBI images, IPCL are shown as dark-brownish lines, and the background mucosa is a light brownish color. The respective RGB band images obtained from the original regular and
Discussion
Since EMR has become established as a therapeutic option for mucosal cancer, the differential diagnosis between mucosal and submucosal cancer in the GI tract has became critical. For squamous cell carcinoma of the esophagus, this differentiation is of particular importance, and such lesions should be subclassified according to microinvasion of the tumor as m1, m2, m3, sm1, sm2, sm3.9 Of all superficial squamous cell carcinomas, m1 or m2 cancers rarely have lymph node metastases and can,
Acknowledgements
We thank Dr. Philip W. Y. Chiu from the Department of Surgery, United Christian Hospital, Hong Kong, for his assistance with preparation of this manuscript.
References (15)
- et al.
Dynamism of tumour vasculature in the early phase of cancer progression: outcomes from oesophageal cancer research
Lancet Oncol
(2002) - et al.
Optimum treatment strategy for superficial esophageal cancer: endoscopic mucosal resection versus radical esophagectomy
World J Surg
(2001) - et al.
Ultra-high magnification endoscopy of the normal esophageal mucosa
Dig Endosc
(1996) - et al.
Ultra-high magnification endoscopic observation of carcinoma in situ of the esophagus
Dig Endosc
(1997) - et al.
Magnifying endoscopy, stereoscopic microscopy, and the microvascular architecture of superficial esophageal carcinoma
Endoscopy
(2002) - Sano Y, Kobayashi M, Hamamoto Y, Kato S, Fu KI, Yoshino T, et al. New diagnostic method based on color imaging using...
- et al.
New diagnostic method based on color imaging using narrow band imaging (NBI) system for gastrointestinal tract
Early Colorectal Cancer
(2001)
Cited by (0)
- ☆
The development of the NBI system was supported by a portion of the grant for the 2nd-Term Comprehensive 10-Year Strategy for Cancer Control in National Cancer Center Hospital East, Japan.