Elsevier

Journal of Cystic Fibrosis

Volume 7, Issue 6, November 2008, Pages 581-584
Journal of Cystic Fibrosis

Short report
Quality of life in patients with Cystic Fibrosis: Association with anxiety and depression

https://doi.org/10.1016/j.jcf.2008.05.010Get rights and content
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Abstract

Background

Few studies of patients with CF have looked at the association between patient reported Health-Related Quality of Life (HRQoL) and anxiety and depression. This study investigated whether CF patients with symptoms of anxiety or depression reported lower Health-Related Quality of Life (HRQoL) scores.

Methods

57 adult CF patients completed the Hospital Anxiety and Depression Scale (HADS) and the Cystic Fibrosis Questionnaire, a CF-specific measure of HRQoL. Analyses of variance with lung function as a covariate were used to investigate differences in HRQoL between groups of patients with and without symptoms of anxiety and depression.

Results

Mean age was 26.7 years (SD 8.1), mean FEV1 %predicted was 65.09 (SD 22.18). Anxiety and depression scores were low and similar to normative scores. After controlling for lung function, patients with symptoms of anxiety reported lower on vitality, emotional functioning, social, treatment burden, health perceptions and respiratory symptoms. Those with depressive symptoms reported lower HRQoL scores for emotional functioning, eating disturbances and body image.

Conclusions

Preliminary evidence was found of the role of anxiety and depression in different areas of quality of life in CF, which may help in the development of appropriate medical and psychosocial treatment programs.

Keywords

Health-related quality of life
Anxiety
Depression

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1

Lieven Dupont is a part-time senior research fellow of the FWO Vlaanderen.