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Original ResearchCOPDPerceptual and Physiologic Responses During Treadmill and Cycle Exercise in Patients With COPD
Section snippets
Subjects
Inclusion criteria were as follows: age ≥ 50 years; diagnosis of COPD12; ≥ 10 pack-year history of cigarette smoking; ability to exercise on the cycle ergometer and treadmill; and clinically stable COPD. Institutional review board approved the study, and written informed consent was obtained from each participant.
Experimental Protocol
Each patient was tested at three visits, separated from each other by 2 to 4 days. At visit 1, the following assessments were made: medical history, vital signs, current medications,
Results
Descriptive characteristics of the 20 patients are given in Table 1. There were no significant differences for postbronchodilator values for lung function at the two visits. Respiratory medications included the following: albuterol metered-dose inhaler (n = 20); inhaled long-acting β-agonist (n = 13); inhaled short- or long-acting anticholinergic medications (n = 15); inhaled corticosteroids (n = 10); and oral theophylline (n = 4).
Physiologic and perceptual results from incremental
Discussion
Our study demonstrates that patients with COPD exhibit different perceptual and physiologic responses during treadmill walking and cycling. The unique findings are as follows: (1) regression slopes between breathlessness as a function of o2 and of Ve are significantly higher on the treadmill than on the cycle ergometer; (2) the onset of breathlessness and leg discomfort occurs at a lower o2 with cycling compared with treadmill walking; and (3) leg discomfort is the predominant symptom
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2020, Respiratory Physiology and NeurobiologyCitation Excerpt :About 6MWT, Deboeck et al demonstrated that patients with pH had higher oxygen consumption in the 6MWT than in CPET with a cycle ergometer (Deboeck et al., 2005). Similarly, when treadmill tests are compared with cycle ergometer tests, several studies demonstrated higher oxygen consumption in the treadmill test (Abrantes et al., 2012; Hsia et al., 2009; Mahler et al., 2011; Murray et al., 2009). Higher oxygen consumption in the IST can be attributed to the orthostatic body position and vertical displacement of the body against gravity.
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2018, Revue des Maladies RespiratoiresIs the six-minute walk test a useful tool to prescribe high-intensity exercise in patients with chronic obstructive pulmonary disease?
2016, Heart and Lung: Journal of Acute and Critical CareCitation Excerpt :The use of the 6MWT to prescribe ET intensity for patients with COPD seemed justified due to the conclusions of a previous study demonstrating no statistical difference when the oxygen consumption (VO2) of the 6MWT was compared with the maximum oxygen consumption (VO2max) achieved in a CPET performed on cycle-ergometer.32 However, as widely known, VO2 and respiratory symptoms are higher when the CPET is performed on a treadmill in comparison to a cycle-ergometer.33–37 Hence, the choice of comparing the metabolic responses of two different activities, i.e., cycling vs. walking, may have biased the conclusion of that study, i.e., that the 6MWT stimulates patients with COPD to a maximum effort.32
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Dr. Baird is Scientific Director of Psychological Applications, LLC, which owns the copyright of the continuous measurement program. The other authors have no conflicts of interest to disclose.