Chest
Clinical Investigations; Articles; Selected ReportsThe Relationship of the 6-Min Walk Test to Maximal Oxygen Consumption in Transplant Candidates With End-Stage Lung Disease
Section snippets
Patient Population
Sixty patients with end-stage lung disease who were undergoing pre-lung transplant evaluation served as subjects. The criteria necessary for transplantation included any end-stage pulmonary condition or disease resulting in frequent hospitalizations, progressive deterioration of pulmonary function, the inability to perform normal daily activities, and a life expectancy of less than 18 months. The patient characteristics are listed in Table 1. Patients with psychological impairment (ie, severe
Exercise Testing and Respiratory Gas Analysis
Several of the variables obtained from the maximal symptom-limited bicycle ergometry exercise tests with respiratory gas analysis are shown in Table 1. There was no significant difference between groups in any of the exercise test variables.
The mean exercise duration of groups A and B was 4.45±1.9 and 4.15 ±2.15 mins, respectively, with a maximal workload of 34.5±22 and 35.7±27 W, respectively. The mean maximal VT of groups A and B was 867±276 and 905 ±308 mL, respectively, with a mean increase
Discussion
The results of this study suggest that the distance ambulated during a 6'WT may predict o2 max in patients with end-stage lung disease. The respectable correlation of distance ambulated during the 6'WT to o2 max and the development of several regression equations to easily predict o2 max in patients with end-stage lung disease are the major contributions of this study. The ability to predict o2 max may be helpful in evaluating patient status, prescribing an effective
Summary
No previous study has evaluated the relationship of the 6'WT to o2 max. This study has shown that the 6'WT total distance ambulated is the strongest independent correlate to o2 max and that it can predict o2 max in patients with end-stage lung disease but accounts for only 54% of the variability. The addition of age and weight, as well as pulmonary function test results (DCO, FEV1, and FVC) did increase the ability to predict o2 max and account for more of the
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