Chest
Original ResearchBronchiectasisBronchiectasis in a Diverse US Population: Effects of Ethnicity on Etiology and Sputum Culture
Section snippets
Study Population
Approval for this study was obtained by the internal review board of the University of Chicago (09-069-B), and all patients provided informed consent. Patients with bronchiectasis were initially identified by International Classification of Diseases, Ninth Edition code or by referral. Patients with cystic fibrosis (CF), emphysema, and interstitial lung disease were excluded.
Clinical Assessment
A clinical questionnaire was administered to each patient, assessing demographics and medications, tobacco and alcohol
Results
HRCT scanning confirmed the presence of bronchiectasis in 114 patients. Two patients declined consent, yielding 112 patients for the initial evaluation. Six patients did not follow up with the evaluation; thus, 106 patients were available for the complete analysis (Fig 1).
Discussion
We describe the etiology of bronchiectasis in 106 patients in a diverse US population. Consistent with previous studies,20 the present population was predominantly women and nonsmokers. Prior investigations into the etiology of bronchiectasis have found that between 26% and 53% of cases are idiopathic.8, 9 In contrast, only 6.6% of the present cases were idiopathic after systematic evaluation. The study population was ethnically diverse, with 40% of non-EA ethnicity. Given the influence of
Acknowledgments
Author contributions: Dr McShane had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Dr McShane: contributed to data collection, organization, and analysis and to the preparation, writing, review, and submission of the manuscript.
Dr Naureckas: contributed to data collection, organization, and analysis and to the preparation, writing, review, and submission of the manuscript.
Dr Strek: contributed to data
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Drs Naureckas and Strek contributed equally to this work.
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Funding/Support: The authors have reported to CHEST that no funding was received for this article.