Chest
Clinical InvestigationsAIRWAY DISEASEThe Relationships Among Pulmonary Function, Aerobic Fitness, and Cognitive Functioning in Older COPD Patients
Section snippets
Participants
Participants were 98 individuals who were taking part in the Reconditioning Exercise and COPD Trial (REACT). The REACT study is an 18-month exercise intervention in which all participants complete 3 months of exercise before being randomly assigned to either return to their normal lifestyle or to continue exercising for an additional 15 months. For the purposes of this study, only data from the initial screening visits were examined. Individuals with COPD were recruited from the community
Results
There were a total of 98 participants in the study, ranging in age from 56 to 80 years old. Of these 98 subjects, data is available for 60 people who completed testing for Fluid, 34 people who completed Speed, 29 people who completed Span, and 31 people who completed Stopping. Descriptive data for each of the subsamples tested is presented in Table 2.
Discussion
It has been proposed that the mechanism underlying the negative relationship between age and cognitive functioning is cerebral oxygenation.3 Further, it has been proposed that an explanation for individual differences in cognitive functioning among older adults may be aerobic fitness level because of its impact on cerebral oxygenation.3 Patients with COPD may have a reduced o2peak for several reasons. These patients may be limited by their cardiovascular system, similar to normal healthy
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Effects of exercise training on cognition in chronic obstructive pulmonary disease: A systematic review
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2015, Heart and Lung: Journal of Acute and Critical CareCitation Excerpt :Persons with HF are known to exhibit reduced fitness due to exercise intolerance secondary to the inability of the heart to meet the demands of the skeletal muscles.33 Poor fitness is a key contributor to cognitive impairment in HF and COPD may contribute to cognitive dysfunction in this population due to its association with poor fitness stemming from diminished pulmonary ventilation and increased rates of physical inactivity.7,13,14 Poor physical fitness is linked with vascular abnormalities (e.g., endothelial dysfunction) that negatively impact cerebral blood flow34,35 and this pattern may translate to insult to the cerebral morphometry.34
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2014, Journal of the American Medical Directors AssociationCitation Excerpt :Our hypothesis that airflow limitation is associated with cognitive impairment in persons with OLD was confirmed. In line with previous studies, which stated that cognitive functioning seems to be positively correlated with increased FEV1 in patients with COPD,18,19 we found a weak correlation between cognitive impairment and FEV1 in persons with OLD. Etnier et al19 found that FVC was a significant predictor of working memory storage in older patients with mild to moderate COPD recruited from the community.19
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2013, Mental Health and Physical ActivityCitation Excerpt :In addition to the positive findings demonstrated among healthy, older adults, several studies have replicated this relationship in clinical populations. Etnier et al. (1999) examined the association between cognitive function and several indices of aerobic capacity in a sample of 98 older adults with chronic obstructive pulmonary disease (COPD). Specifically, the authors investigated whether measures of fluid intelligence, processing speed and working memory, or processing speed and inhibition were associated with different indices of cardiovascular and cardiopulmonary function, including the 6-min walk test, peak VO2, and FEV1.
Balance impairment and cognitive dysfunction in patients with chronic obstructive pulmonary disease under 65 years
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2020, Neurovascular Neuropsychology: Second Edition
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Currently at the Department of Exercise Science and Physical Education, Arizona State University, Tempe, AZ. Supported by National Institutes of Health grant HL 53755.