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Clinical InvestigationsBRONCHOSCOPYDiagnostic Yield of Fiberoptic Bronchoscopy in Evaluating Solitary Pulmonary Nodules
Section snippets
Materials and Methods
We retrospectively reviewed the medical records of all patients who underwent bronchoscopy at the Houston Veterans Affairs Medical Center (HVAMC) between January 1992 and August 1996. One hundred seventy-seven patients met the following criteria for inclusion in the study: (1) presence of a single circumscribed lung mass completely surrounded by aerated lung without associated abnormalities (including atelectasis, pneumonitis, satellite lesions, or cavity); (2) lesions that were not visible
Results
One hundred seventy-seven patients fulfilled the inclusion criteria and were enrolled in the study. They were all men (mean age, 65 ± 8 years; range, 41 to 83 years), and were all active or ex-smokers (mean, 59 ± 23 pack-years; range, 24 to 126 pack-years).
One hundred fifty-one lesions were malignant (80 adenocarcinoma, 58 squamous cell carcinoma, 3 undifferentiated nonsmall cell carcinomas, 6 small-cell carcinomas, and 4 carcinoid tumors). Twenty-six lesions were benign (12 noncaseating
Discussion
Although multiple studies have investigated factors affecting diagnostic yield in FFB, only seven English-language studies have addressed SPNs (Table 1). Diagnostic yields in SPN studies ranged from 18 to 62%. In the study by Torrington and Kern,2 SPNs were poorly characterized and were defined only as meeting criteria for stage I carcinomas (T1N0M0 or T2N0M0). Thus, there was no upper limit for the size of lesions, and it is uncertain whether lesions that were pleural based or had associated
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