Chest
Original ResearchPulmonary ProceduresComplications, Consequences, and Practice Patterns of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Results of the AQuIRE Registry
Section snippets
Materials and Methods
All patients undergoing bronchoscopy with lymph node sampling by TBNA at six centers from February 13, 2009, to August 31, 2010, were entered consecutively into AQuIRE at the time of their procedure.20 Institutional review board approval was obtained at each site (e-Appendix 1). Informed consent or a waiver of consent was obtained in accordance with institutional guidelines. Data were entered through the AQuIRE Web-based interface using standardized definitions, quality control checks, and
Results
A total of 1,317 patients were enrolled by 12 physicians from six hospitals. Baseline patient characteristics are summarized in Table 1.
Discussion
To our knowledge, this is the first report of EBUS-TBNA complications and consequences from a multicenter registry. It shows that EBUS-TBNA is a reassuringly safe procedure with an overall complication rate of only 1.4% in participating centers. The complications noted were most often secondary to concurrent TBBx. Escalations in level of care resulting from these complications were more frequent in older patients, inpatients, and patients receiving deep sedation or general anesthesia. Also to
Acknowledgments
Author contributions: Dr Eapen had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Dr Eapen: contributed as the principal investigator (PI) for this study and to project oversight and organization, data collection, and manuscript writing.
Dr Shah: contributed to the study design, data collection and auditing, and writing of the manuscript.
Dr Lei: contributed as the primary biostatistician for the project and
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Funding/Support: This research was supported in part by the National Institutes of Health through a Cancer Center Support Grant [CA016672] to The University of Texas MD Anderson Cancer Center. The AQuIRE database is funded by the American College of Chest Physicians.
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