Chest
Preliminary ReportPulmonary Function and Sputum Production in Patients With Cystic Fibrosis: A Pilot Study Comparing the PercussiveTech HF Device and Standard Chest Physiotherapy
Section snippets
Materials and Methods
The study was approved by the Human Use Committee of Bronson Methodist Hospital. Informed consent was obtained from all participants and the parents/guardians of those patients < 18 years old.
Ten participants recruited from the Cystic Fibrosis Center at Michigan State University/Kalamazoo Center for Medical Studies had a diagnosis of CF confirmed by clinical history, physical examination, and sweat chloride level ≥ 60 mEq/L and/or genetic testing. Patients were included if they were clinically
Results
Nine participants completed the study. Participant demographics are shown in Table 1. One patient was excluded after having minor hemoptysis following CPT. All participants had mild-to-moderate disease severity. All tolerated both treatments with no significant oxyhemoglobin desaturation (data not shown). Mean pulmonary function and wet and dry sputum weight results are shown in Table 2. No PFT parameters were significantly changed at 4 h after CPT or PTHF, although there was a trend to
Discussion
This is the first clinical study of the PTHF device compared to standard CPT. Although a small, single-intervention pilot study, we feel it demonstrates the short-term safety and efficacy of the PTHF device. We have previously studied the Flutter device and the IPV in patients with CF.345 These airway clearance devices utilize oscillating positive pressure delivered to the airway to enhance clearance of airway secretions. In two short-term studies, we found no difference in sputum production
References (12)
- et al.
Recent advances in the treatment of cystic fibrosis
Pediatr Clin North Am
(1994) - et al.
Comparison of intrapulmonary percussive ventilation and chest physiotherapy: a pilot study in patients with cystic fibrosis
Chest
(1994) - et al.
Efficacy of the flutter device for airway mucus clearance in patients with cystic fibrosis
J Pediatr
(1994) - et al.
Sputum rheology changes in cystic fibrosis lung disease following two different types of physiotherapy: flutter vs autogenic drainage
Chest
(1998) - et al.
Role of conventional physiotherapy in cystic fibrosis
J Pediatr
(1988) - et al.
The intrapulmonary percussive ventilator and flutter device compared to standard chest physiotherapy in patients with cystic fibrosis
Clin Pediatr
(1998)
Cited by (0)
Presented at the Thirteenth Annual North American Cystic Fibrosis Conference, Seattle, Washington, October, 1999.
Supported by a research grant from Vortran Medical Technology 1, Sacramento, CA.