Chest
Clinical InvestigationsDevelopment and Validation of a Survey-Based COPD Severity Score
Section snippets
Overview
In a population-based sample of 383 US adults with COPD, we developed a disease-specific COPD severity instrument. The severity score was based on responses to a structured telephone interview. Internal consistency reliability was established using standard psychometric techniques. We evaluated concurrent validity by examining the association between the COPD severity score and three aspects of health status: pulmonary function, physical HRQL and health status, and physical disability.
Subject Characteristics
The mean age of subjects with COPD was 64 ± 6 years (Table 2). The majority of subjects had a lifetime history of cigarette smoking (81%). Other sociodemographic characteristics are shown in Table 2.
COPD Severity Score
The COPD severity score ranged from 0 to 28 (mean, 7.3 ± 6.5; median, 6.0; 25th to 75th interquartile range, 2 to 25). The COPD severity score, which was based on an a priori weighting system, correlated very closely with the score whose alternative weighting was derived from factor analysis with
Discussion
In this population-based study, we developed a survey-based COPD severity score that incorporates clinical aspects of the disease, including respiratory symptoms, oral corticosteroid use, other COPD medication use, previous hospitalization and intubation, and home oxygen therapy. The COPD severity score is internally consistent, reliable, and appears to capture a broad range of disease severity. We have demonstrated the concurrent validity of the COPD severity score using diverse measures of
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2014, ChestCitation Excerpt :Physician-diagnosed COPD was defined as a positive response to chronic bronchitis, emphysema, and/or COPD prior to or on admission to the hospital.9,22,23 We defined COPD via self-report because multiple previous studies have shown that self-reported, physician-diagnosed COPD is highly consistent with spirometry-diagnosed COPD and accurate for epidemiologic studies.24–26 In total, 902 patients with early-stage NSCLC were included in this study.
Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestjournal.org/misc/reprints.shtml).
Support was provided by grant R01 HL607438 from the National Heart, Lung, and Blood Institute, National Institutes of Health, and Flight Attendants Medical Research Institute grant CoE2001. Dr. Eisner was also supported by grant K23 HL04201 from the National Heart, Lung, and Blood Institute.